Clomiphene is used to induce ovulation (production of eggs) in women who have not produced eggs (eggs) but wish to become pregnant (infertile). Clomiphene belongs to a group of drugs known as ovulation-stimulating drugs. It works similarly to estrogen, a female hormone that causes eggs to develop and release in the ovaries.
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How to use clomiphene citrate?
Clomiphene must be taken exactly as prescribed by your doctor to be most effective. The following procedures can be used to monitor induction cycles: Follicle monitoring by vaginal ultrasound, starting to 6 days after the last pill. Serial
transvaginal ultrasound can reveal the size and number of developing cysts. It can also provide presumptive
evidence of ovulation such as sudden collapse of the preovulatory follicle and increased fluid volume in the uterine sac. After ovulation, it may exhibit signs of lutealization
such as loss of well-defined
follicular margins and presence
of internal echoes. Serum estradiol levels, starting -6 days after the last pill Increased urine LH concentration
Test for LH elevation in urine 3- days after last dose of clomiphene Post-ovulation test 1-3 days before ovulation to check for at least 5 progressive sperms per HPF Mid-luteal
progesterone, with at least 10 ng/ml 7-9
days after ovulation is considered
sufficient. Clomiphene activates
the pituitary gland in the brain
to secrete increased amounts of follicle-stimulating hormone (FSH) and
LH (luteal hormone). This action
stimulates the growth of the follicle and thus the initiation of ovulation. During a normal menstrual cycle, only one egg is released.
Clomiphene is used to induce ovulation (production of eggs) in women who have not produced eggs (eggs) but wish to become pregnant (infertile). Clomiphene belongs to a group of drugs known as
ovulation-stimulating drugs. It works similarly to estrogen, a female
hormone that causes eggs to develop and
release in the ovaries.
Clomiphene citrate is an oral medication that induces ovulation by blocking
estrogen receptors. This artificial anti-estrogen effect tricks your body into believing that estrogen levels
are low, which stimulates the production of more follicle-stimulating hormone (FSH). Clomiphene improves the
chances of pregnancy for most
women who ovulate irregularly
and with less risk of dangerous
side effects. In addition to ovulation,
clomiphene is also used along
with intrauterine insemination to treat
unexplained infertility. This medication is used to treat infertility in women.
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How does
Clomiphene work?
It works
by stimulating an increase in the amount of a hormone that aids in
the development and release of a
mature egg (ovulation). This medicine
is not recommended for women whose ovaries are no longer producing
eggs correctly (primary
pituitary or ovarian failure). If three to six Clomid cycles do not result
in pregnancy, new treatment options may be considered. Six cycles of
Clomid is considered the upper
limit, although some health care providers suggest continuing if pregnancy does not occur before the third cycle of
treatment.
Clomiphene is used to induce ovulation in women with certain medical conditions (such as
polycystic ovary syndrome) that prevent the
natural process of ovulating. Side Effects Abdominal discomfort, bloating, abdominal/pelvic bloating, flushing ("hot
flashes"), breast tenderness, headache, or dizziness may occur. If any of
these effects persist or get
worse, tell your doctor or pharmacist right
away. Changes in vision
(such as blurred, patchy, or flickering vision) can sometimes occur
during treatment with clomiphene,
especially if you are exposed to bright light. These side effects usually go
away days or weeks after stopping
treatment.
Enclomiphene citrate is effective in increasing serum testosterone levels in hypogonadal men, as well as maintaining sperm count. Enclomiphene is used to increase serum total testosterone levels while maintaining sperm counts within normal limits in men with secondary hypogonadism. Enclomiphene is a Selective Estrogen Receptor Modulator (SERM) for the treatment of female infertility.
It works by promoting the release of reproductive
hormones. This helps stimulate ovulation
from the ovaries (ovulation).
Clomiphene citrate has been used off-label to increase luteinizing hormone
(LH), follicle-stimulating hormone (FSH), and testosterone (T) in men with
secondary hypogonadism. A newer agent, enclomiphene citrate, is a trans isomer of clomiphene citrate
and is being investigated for use in men
with hypogonadism. Enclomiphene citrate is a potent and orally active estrogen receptor antagonist with antiestrogenic properties.
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